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In a recently published article in the peer-reviewed journal Vaccines, PGS report on the immune responses elicited by mucosal homologous plasmid and a heterologous immunization strategy using a plasmid vaccine and a Modified Vaccinia Ankara (MVA) expressing SARS-CoV-2 spike (S) and nucleocapsid (N) antigens.  Abstract The rapid transmission of SARS-CoV-2 in the USA and worldwide…

“A COVID-19 vaccine being developed by UW-Madison microbiology professor Adel Talaat and his Madison startup, Pan Genome Systems, is adapted from an experimental DNA-based immunization Talaat developed for another coronavirus that infects chickens. The human version has shown promise in mice, according to a study published in February in the journal Vaccines.versity of Wisconsin (UW)–Madison houses an important…

Drs. Yashdeep Phanse and Adel Talaat recently received a Phase I SBIR grant from the United States Department of Agriculture (USDA) to further develop and commercialize their novel Infectious Bronchitis virus (IBV) vaccine. Infectious Bronchitis (IB) is an economically important severe respiratory infectious disease of poultry caused by an avian coronavirus, IBV. The USA animal…

A new study published in the journal “Microorganisms” shows that PGS’ live attenuated vaccine against Johne’s disease can induce a robust T cell immune response in a safe fashion and minimize fecal shedding when tested in cattle. This vaccine has been successfully tested in mice and goats previously. Abstract: Johne’s disease (JD) caused by Mycobacterium avium subsp. paratuberculosis (M.…