PGS used a propriety mosaic sequence of multiples isolates of highly pathogenic isolates of Avian Influenza to develop a protective vaccine with almost sterilizing immunity that can benefit poultry flocks. This vaccine targets both low and high pathogenicity isolates of Avian Influenza. See the details in the following article:
Effective mosaic-based nanovaccines against avian influenza in poultry. Kingstad-Bakke BA, Chandrasekar SS, Phanse Y, Ross KA, Hatta M, Suresh M, Kawaoka Y, Osorio JE, Narasimhan B, Talaat AM. Vaccine. 2019 Aug 14;37(35):5051-5058. doi: 10.1016/j.vaccine.2019.06.077.