Pan Genome Systems

Developing patent-protected vaccines and diagnostics to fight animal and human infectious diseases.

Our Vision

Provide more effective and safer vaccines to fight infectious diseases important for animal and human health.

Pan Genome Systems Focus on livestock (cattle, camels, sheep, goats) and Poultry Health Products. We also help other strategic partners in testing their products.

What We Do

Pan Genome Systems develops and delivers novel, patent-protected vaccines and diagnostics directed to control Johne’s disease in Cattle, Avian Influenza and Avian Coronavirus (Infectious Bronchitis Virus) in Poultry. We also provide research services to help others in developing their own products after signing the appropriate agreements.

Pan Genome Systems' products and services are helpful to other researchers, farmers, technicians, veterinarians and veterinary labs.

We treat every customer as our partner. Our success is your success.

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Pan Genome Systems' products are born of world-class science. Our core technology has been developed and honed over 15 years of laboratory research, and commercial development.

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The Next Generation in Vaccines

Our Products

Johne’s disease (Paratuberculosis) vaccines

Avian Influenza vaccines

Infectious Bronchitis Virus Vaccines

Various testing services to strategic partners with appropriate agreements


Our Product Promise


The safety of our products is paramount. We have carefully created products with both animals and farmers in mind, putting product safety first.


Our single-dose vaccines are easily administered on the farm and maximize protection while reducing workload for busy farmers.


Detailed studies, in the laboratory, in controlled conditions, and in the field, have proven the effectiveness of our products to reduce infections, reduce disease spread, and reduce side-effects.


Our products have been subject to the most rigorous of laboratory and field testing by world-leading scientists, industry experts, and real farmers over years of product testing and development.

Our People

Management Team

Dr. Adel Talaat, Ph.D Chairman/CEO

Dr. Yashdeep Phanse, Ph.D Director of Scientific Operations

Board of Directors

Dr. Adel Talaat, Ph.D Chairman/CEO

Dr. Bill Checovich, Ph.D Director of Operations, Global Consumables Illumina Corporation 

Board Member

Dr. Michael T. Collins, DVM, Ph.D, DACVM Board Member


PGS’ COVID-19 vaccine research published in the journal- Vaccines

By PAN GENOME SYSTEMS | March 21, 2021

In a recently published article in the peer-reviewed journal Vaccines, PGS report on the immune responses elicited by mucosal homologous plasmid and a heterologous immunization strategy using a plasmid vaccine and a Modified Vaccinia Ankara (MVA) expressing SARS-CoV-2 spike (S) and nucleocapsid (N) antigens.  Abstract The rapid transmission of SARS-CoV-2 in the USA and worldwide…

Madison companies still pursuing COVID-19 vaccines

By PAN GENOME SYSTEMS | March 21, 2021

“A COVID-19 vaccine being developed by UW-Madison microbiology professor Adel Talaat and his Madison startup, Pan Genome Systems, is adapted from an experimental DNA-based immunization Talaat developed for another coronavirus that infects chickens. The human version has shown promise in mice, according to a study published in February in the journal Vaccines.versity of Wisconsin (UW)–Madison houses an important…

Pan Genome Systems receives USDA Small Business Innovation Research (SBIR) grant to develop vaccines against avian coronaviruses

By PAN GENOME SYSTEMS | March 21, 2021

Drs. Yashdeep Phanse and Adel Talaat recently received a Phase I SBIR grant from the United States Department of Agriculture (USDA) to further develop and commercialize their novel Infectious Bronchitis virus (IBV) vaccine. Infectious Bronchitis (IB) is an economically important severe respiratory infectious disease of poultry caused by an avian coronavirus, IBV. The USA animal…

Pan Genome Systems develops a protective vaccine against Johne’s disease in Cattle

By PAN GENOME SYSTEMS | September 9, 2020

A new study published in the journal “Microorganisms” shows that PGS’ live attenuated vaccine against Johne’s disease can induce a robust T cell immune response in a safe fashion and minimize fecal shedding when tested in cattle. This vaccine has been successfully tested in mice and goats previously. Abstract: Johne’s disease (JD) caused by Mycobacterium avium subsp. paratuberculosis (M.…


Inventor: Adel M. Talaat, Bassam Abomoelak and Sarah K. Ward. Immunogenic Compositions Against Tuberculosis. US 8,367,055 B2. (Issued)

Inventor: Adel M. Talaat. Vaccine Candidates Against Johne’s Disease. US 8,758,77

Inventor: Adel M. Talaat. Global gene regulators (GGR) as vaccine candidates against paratuberculosis. US 10,544,389 (Issued)

Inventor: Adel M. Talaat. RNA Biomarkers for Early Diagnosis of Mycobacterial Infections. WARF: P130075US01 (Pending)

Inventor: Adel M. Talaat and Sekar Chandrasekar. WARFplex: A novel adjuvant for animal and human vaccines. WARF: P190189 (Pending).

Inventor: Adel M. Talaat and Brock Bakke. A universal vaccine against Infectious Bronchitis Virus, Avian Influenza, Newcastle Disease Virus and Infectious Bursal Disease. WARF: P190239 (Pending).

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